It was noticed by Milgrom (1983) that the transition yellow to orange always occurs at an orbital acceleration of 2x10^-10 m/s^2. This is also true by the way of globular clusters that dark matter cannot be applied to. The wavelength of Unruh radiation depends on acceleration (a) as follows: wavelength~8c^2/a. For stars in the yellow the orbital acceleration (a=v^2/r) is high, so the Unruh wavelength is short (shown by the bottom red sine wave). As you go radially outwards, the orbital acceleration drops, so the Unruh waves lengthen (see the second red wave from the bottom). Near the point where the stars start to misbehave the Unruh waves become as long as the Hubble scale (see the two upper red curves). Milgrom noticed this telling link between dynamics and cosmology but could not explain it in his MoND model (this critical acceleration has to be input by hand) and if you try the numbers: wavelength = 8c^2/(2x10^-10) = 36x10^26m you'll see the predicted Unruh wavelength is 14 times larger than the Hubble scale which is 2.6x10^26 m.
MiHsC specifically explains this dynamics-cosmology link, and although it predicts a different critical acceleration (a=6.9x10^-10 m/s^2), the point is: it predicts it! MiHsC says that the inertial mass of objects is caused when they accelerate and an information horizon forms damping Unruh radiation, making it vary in space, and so able to push to oppose the initial acceleration. However, only Unruh waves that fit exactly (resonate) within the Hubble horizon are allowed (those with nodes at the horizon, see the diagram). The logic is that partial waves would allow us to infer something outside the horizon (that part of the wave) which would defeat the purpose of the horizon. So, as the Unruh waves lengthen, a lesser proportion of them are allowed (it is rather like a Hubble-scale Casimir effect) so the outer stars' Unruh-radiation-induced inertial mass collapses, they feel less centrifugal force, and so they can orbit much faster without the galaxy exploding. In this way MiHsC predicts galaxy rotation, with no dark matter needed.
The fact that the Unruh wavelength stars see when they start to misbehave in galaxies is equal to the observed distance to the Hubble horizon, is a direct indication of MiHsC. A smoking gun in every galaxy. Something that the ad hoc dark matter hypothesis can never hope to achieve.
Milgrom, M., 1983. ApJ, 270, 365.
McCulloch, M.E., 2007. MNRAS, 376, 338-342. https://arxiv.org/abs/astro-ph/0612599